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MORF4L1 Produits

(Mortality Factor 4 Like 1 (MORF4L1))

Catégories

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).

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Catégories MORF4L1 en vedette

MORF4L1 Anticorps

High quality antibodies with extensive validation data.

MORF4L1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MORF4L1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, IHC
Validations
  • (6)
N° du produit ABIN185075
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (1)
  • (4)
N° du produit ABIN2777616
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7239452
Quantité 200 μL
Fiche technique Fiche technique

MORF4L1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231386
Quantité 96 tests
Fiche technique Fiche technique

MORF4L1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124021
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311164
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311162
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MORF4L1

Chen, Li, Dunn, Xiong, Chen, Zhao, Chen, Mallampalli, Zou: "Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization." dans: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 7092-8, (2014) (PubMed).

Xie, Pelz, Wang, Bashar, Varlamova, Shadle, Impey: "KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription." dans: The EMBO journal, Vol. 30, Issue 8, pp. 1473-84, (2011) (PubMed).

Pardo, Leung, Lucchesi, Pereira-Smith: "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation." dans: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50860-6, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à MORF4L1

mortality factor 4 like 1 (MORF4L1), mortality factor 4 like 1 (Morf4l1), MORF-related gene 15 (MRG15), MRG15 (CpipJ_CPIJ013367), mortality factor 4 like 1 S homeolog (morf4l1.S), mortality factor 4 like 1 (morf4l1), CG6363, Dmel\\CG6363, DmMRG15, Dmrg15, dMRG15, dMrg15, Eaf3, HsT17725, l(3)j6A3, MEAF3, mKIAA4002, MORF4L2, MORFRG15, MRG15, Mrg15, S863-6, TEG-189, Tex189, zgc:92289

Protein level used designations for MORF4L1

  • Esa1p-associated factor 3 homolog
  • MORF-related gene 15 protein
  • MORF-related gene on chromosome 15
  • mortality factor 4-like protein 1
  • protein MSL3-1
  • transcription factor-like protein MRG15
  • testis expressed gene 189
  • testis-expressed gene 189 protein
  • MORF-related gene 15
  • mortality factor 4 like 2
  • CG6363-PA
  • CG6363-PB
  • MRG15-PA
  • MRG15-PB
  • MRG15
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