This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010].
custom-made
MTMR14
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
MTMR14
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
MTMR14
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MTMR14
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Papp, Kovács, Billes, Varga, Tarnóci, Hackler, Puskás, Liliom, Tárnok, Schlett, Borsy, Pádár, Kovács, Hegedűs, Juhász, Komlós, Erdős, Gulyás, Vellai: "AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects." dans: Autophagy, Vol. 12, Issue 2, pp. 273-86, (2016) (PubMed).
Pseudonymes pour MTMR14 Protéines
myotubularin related protein 14 (mtmr14) Protéines myotubularin-related protein 14 (LOC703936) Protéines myotubularin related protein 14 S homeolog (mtmr14.S) Protéines myotubularin related protein 14 (MTMR14) Protéines myotubularin related protein 14 (Mtmr14) Protéines 1110061O04Rik Protéines AW553738 Protéines C3orf29 Protéines C76151 Protéines fc14d11 Protéines jumpy Protéines MGC131146 Protéines RGD1304842 Protéines wu:fc14d11 Protéines