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MUC1 Produits

(Mucin 1 (MUC1))

Catégories

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].

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Catégories MUC1 en vedette

MUC1 Anticorps

High quality antibodies with extensive validation data.

MUC1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MUC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MUC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (7)
N° du produit ABIN7440383
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (8)
N° du produit ABIN7442027
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, WB, ELISA, FACS, ICC, Neut
Validations
  • (6)
N° du produit ABIN5611324
Quantité 0.1 mg
Fiche technique Fiche technique

MUC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (5)
N° du produit ABIN6730894
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968677
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968678
Quantité 96 tests
Fiche technique Fiche technique

MUC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275298
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1311631
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7013439
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MUC1

El-Rasikh, Farghali, Abdelrahman, Elgaffary, Abdelmalek, Emam, Ghoneim, Selim: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." dans: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).

Saleh, Harb, Soudani, Zaraket: "A three-dimensional A549 cell culture model to study respiratory syncytial virus infections." dans: Journal of infection and public health, Vol. 13, Issue 8, pp. 1142-1147, (2020) (PubMed).

Szlendak, Sitarz, Berbecka, Mielko, Morsink, Maciejewski, Offerhaus, Polkowski: "Expression of cyclooxygenase-2 and mucin 1 in colorectal cancer." dans: Molecular and clinical oncology, Vol. 13, Issue 5, pp. 52, (2020) (PubMed).

Zhang, Ji, Liu, Xu: "MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway." dans: Journal of cellular physiology, (2019) (PubMed).

Milara, Díaz-Platas, Contreras, Ribera, Roger, Ballester, Montero, Cogolludo, Morcillo, Cortijo: "MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease." dans: Respiratory research, Vol. 19, Issue 1, pp. 226, (2019) (PubMed).

Reuter, Alzheimer, Walles, Oelschlaeger: "An adherent mucus layer attenuates the genotoxic effect of colibactin." dans: Cellular microbiology, Vol. 20, Issue 2, (2018) (PubMed).

Wang, Lu, Xie, Xiong, Huang, Wei, Jiang, Peng: "Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7." dans: International immunopharmacology, Vol. 58, pp. 64-71, (2018) (PubMed).

Li, Zhou, Wei, Chen, Geng, Zheng, Chai, Li, Jiang: "miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor." dans: Scientific reports, Vol. 6, pp. 27914, (2018) (PubMed).

Wang, Yuan, Wang, Yang, Chen, Liu, Song, Feng, Tan, Jia: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." dans: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).

Wang, Duan, Wu, Min, Huang, Luo, He: "Effect of cyclooxygenase‑2 inhibition on the development of post‑traumatic stress disorder in rats." dans: Molecular medicine reports, Vol. 17, Issue 4, pp. 4925-4932, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à MUC1

mucin 1, cell surface associated (MUC1), mucin 1, cell surface associated (Muc1), mucin 1, transmembrane (Muc1), CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM

Protein level used designations for MUC1

  • DF3 antigen
  • H23 antigen
  • breast carcinoma-associated antigen DF3
  • cancer antigen 15-3
  • carcinoma-associated mucin
  • episialin
  • krebs von den Lungen-6
  • mucin 1, transmembrane
  • mucin-1
  • peanut-reactive urinary mucin
  • polymorphic epithelial mucin
  • tumor associated epithelial mucin
  • tumor-associated epithelial membrane antigen
  • tumor-associated mucin
  • endometrial mucin-1
  • epithelial mucin
  • MUC-1
  • Mucin1
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