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MVP Produits

(Major Vault Protein (MVP))
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].

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Catégories MVP en vedette

MVP Anticorps

High quality antibodies with extensive validation data.

MVP Kits ELISA

Reliable ELISA kits for a wide range of species.

MVP Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MVP recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
N° du produit ABIN564285
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7074548
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7441988
Quantité 100 μL
Fiche technique Fiche technique

MVP recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957625
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN770995
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
N° du produit ABIN777229
Quantité 96 tests
Fiche technique Fiche technique

MVP recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1311678
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123832
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094021
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MVP

Bornachea, Benitez-Amaro, Vea, Nasarre, de Gonzalo-Calvo, Escola-Gil, Cedo, Iborra, Martínez-Martínez, Juarez, Camara, Espinet, Borrell-Pages, Badimon, Castell, Llorente-Cortés: "Immunization with the Gly1127-Cys1140 amino acid sequence of the LRP1 receptor reduces atherosclerosis in rabbits. Molecular, immunohistochemical and nuclear imaging studies." dans: Theranostics, Vol. 10, Issue 7, pp. 3263-3280, (2020) (PubMed).

Zhou, Lin, Zhang, Zhang, Zhang, Zhang, Xie, Ren: "miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression." dans: Cell proliferation, Vol. 50, Issue 3, (2017) (PubMed).

de Gonzalo-Calvo, López-Vilaró, Nasarre, Perez-Olabarria, Vázquez, Escuin, Badimon, Barnadas, Lerma, Llorente-Cortés: "Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study." dans: BMC cancer, Vol. 15, pp. 460, (2016) (PubMed).

Zhang, Neo, Gunaratne, Poulsen, Boping, Ong, Sangthongpitag, Pendharkar, Hill, Cohen: "Feedback regulation on PTEN/AKT pathway by the ER stress kinase PERK mediated by interaction with the Vault complex." dans: Cellular signalling, Vol. 27, Issue 3, pp. 436-42, (2015) (PubMed).

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Pan, Lin, Ma, Shen, Schachner: "Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish." dans: The European journal of neuroscience, Vol. 37, Issue 2, pp. 203-11, (2013) (PubMed).

Rahimi, Wilson, Saylor, Stelow, Thomas, Reibel, Levine, Shonka, Jameson, Read: "p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy." dans: International journal of otolaryngology, Vol. 2012, pp. 685951, (2012) (PubMed).

Wang, Subramanian, Lu, Howatt, Moorleghen, Charnigo, Cassis, Daugherty: "Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms." dans: Atherosclerosis, Vol. 220, Issue 2, pp. 375-80, (2012) (PubMed).

Dortet, Mostowy, Samba-Louaka, Louaka, Gouin, Nahori, Wiemer, Dussurget, Cossart: "Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagy." dans: PLoS pathogens, Vol. 7, Issue 8, pp. e1002168, (2011) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à MVP

major vault protein (MVP), major vault protein (Mvp), major vault protein (mvp), major vault protein L homeolog (mvp.L), major vault protein (Tc00.1047053510353.10), major vault protein (Tb927.5.4460), major vault protein (Tb10.70.0520), major vault protein (Tb10.70.5840), putative major vault protein (LMJF_05_0060), 2310009M24Rik, cb771, LRP, MGC145641, mvp, Tb05.45E22.810, VAULT1, wu:fb52b05, wu:fc02g01

Protein level used designations for MVP

  • lung resistance-related protein
  • major vault protein
  • lung resistance-associated protein
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