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NAPRT1 Produits

(Nicotinate phosphoribosyltransferase (NAPRT))

Catégories

Nicotinic acid (NA\; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT\; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]..

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Catégories NAPRT1 en vedette

NAPRT1 Anticorps

High quality antibodies with extensive validation data.

NAPRT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NAPRT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC, WB
Validations
  • collections(3)
N° du produit ABIN6263515
Quantité 100 μL
Reactivity Human
Application WB
Validations
  • collections(2)
N° du produit ABIN1881564
Quantité 400 μL
Reactivity Human
Application IP, WB
Validations
  • collections(2)
N° du produit ABIN949786
Quantité 100 μL

NAPRT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231618
Quantité 96 tests

NAPRT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • collections(1)
N° du produit ABIN3086350
Quantité 1 mg
Reactivity Mouse
Source Insect Cells
Validations
  • collections(1)
N° du produit ABIN3125863
Quantité 1 mg
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • collections(1)
N° du produit ABIN2726822
Quantité 50 μg

Dernières publications sur nos produits NAPRT1

Gaudino, Manfredonia, Managò, Audrito, Raffaelli, Vaisitti, Deaglio: "Subcellular Characterization of Nicotinamide Adenine Dinucleotide Biosynthesis in Metastatic Melanoma by Using Organelle-Specific Biosensors." dans: Antioxidants & redox signaling, Vol. 31, Issue 15, pp. 1150-1165, (2019) (PubMed).

Managò, Audrito, Mazzola, Sorci, Gaudino, Gizzi, Vitale, Incarnato, Minazzato, Ianniello, Varriale, DAuria, Mengozzi, Politano, Oliviero, Raffaelli, Deaglio: "Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation." dans: Nature communications, Vol. 10, Issue 1, pp. 4116, (2019) (PubMed).

Shames, Elkins, Walter, Holcomb, Du, Mohl, Xiao, Pham, Haverty, Liederer, Liang, Yauch, OBrien, Bourgon, Koeppen, Belmont: "Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 24, pp. 6912-23, (2013) (PubMed).

Xiao, Elkins, Durieux, Lee, Oeh, Yang, Liang, DelNagro, Tremayne, Kwong, Liederer, Jackson, Belmont, Sampath, OBrien: "Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618." dans: Neoplasia (New York, N.Y.), Vol. 15, Issue 10, pp. 1151-60, (2013) (PubMed).

Fagerberg, Stadler, Skogs, Hjelmare, Jonasson, Wiking, Abergh, Uhlén, Lundberg: "Mapping the subcellular protein distribution in three human cell lines." dans: Journal of proteome research, Vol. 10, Issue 8, pp. 3766-77, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à NAPRT1

nicotinate phosphoribosyltransferase (NAPRT), nicotinate phosphoribosyltransferase (Naprt), nicotinate phosphoribosyltransferase (naprt), 9130210N20Rik, PP3856, zgc:77870

Protein level used designations for NAPRT1

  • FHA-HIT-interacting protein
  • NAPRTase
  • nicotinate phosphoribosyltransferase
  • nicotinate phosphoribosyltransferase domain-containing protein 1
  • nicotinic acid phosphoribosyltransferase
  • nicotinate phosphoribosyltransferase-like protein
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