N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Produits
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
Catégories
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 en vedette
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Anticorps
High quality antibodies with extensive validation data.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7434806
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
N° du produit
ABIN513533
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7142987
Quantité
100 μL
Fiche technique
Fiche technique
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958012
Quantité
96 tests
Fiche technique
Fiche technique
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1345778
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124089
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345780
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." dans: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).: "The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro." dans: Cytotechnology, Vol. 70, Issue 1, pp. 387-396, (2018) (PubMed).
: "Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION." dans: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2422-34, (2016) (PubMed).
: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." dans: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." dans: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." dans: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).
: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." dans: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).
: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." dans: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).
: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." dans: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).
: "Clinical utility of serum autoantibodies detected by protein microarray in melanoma." dans: International journal of proteomics, Vol. 2011, pp. 413742, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
N-acylsphingosine amidohydrolase 1 (ASAH1), N-acylsphingosine amidohydrolase 1 (Asah1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L), N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a), Acid ceramidase (asah-1), N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b), 2310081N20Rik, AC, ACDase, ASAH, Asah, asah1, ASAH1, MGC82286, PHP, PHP32, SMAPME, zgc:66026, zgc:101637Protein level used designations for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
- acid CDase
- acid ceramidase
- acylsphingosine deacylase
- putative 32 kDa heart protein
- ACDase
- Acylsphingosine deacylase
- N-acylsphingosine amidohydrolase 1
- AC
- N-acylsphingosine amidohydrolase (acid ceramidase) 1
- N-acylsphingosine amidohydrolase
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