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neonatal Fc Receptor Protéines

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

33 Résultats

FcRn Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274675
 
FcRn Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274677
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274676
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
N° du produit ABIN7536880
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR
N° du produit ABIN7536879
 
FcRn Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Pubmed 1 reference
N° du produit ABIN1353903
 
FcRn Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 3 références
N° du produit ABIN2181081
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 6 références
N° du produit ABIN2181085
 
FcRn Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Pubmed 2 références
N° du produit ABIN2870741
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 1 reference
N° du produit ABIN2870550
 
FcRn Origine: Souris Hôte: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS
N° du produit ABIN5854760
 
FcRn Origine: Rat Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Pubmed 1 reference
N° du produit ABIN2181083
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
N° du produit ABIN2720989
 
FcRn Origine: Rat Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2870582
 
FcRn Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2870570
 
FcRn Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Pubmed 1 reference
N° du produit ABIN2870526
 
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2444126
 
FcRn Origine: Rat Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7583297
 
FcRn Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN2115488
 
FcRn Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
N° du produit ABIN7580616
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
    • Immunogen (Imm)
    • Size-exclusion chromatography-High Pressure Liquid Chromatography (SEC-HPLC)
    • Surface Plasmon Resonance (SPR)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Positive Control (PC)
  • Réactivité
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rhesus Monkey
    • Pig
  • Cité dans publications
  • Images disponible
  • Sans conservateur uniquement
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Human Cells
    • Wheat germ
  • Epitope
    • AA 24-297
    • AA 22-297
    • AA 23-298
    • Extracellular
    • Transcript Variant 2
    • AA 16-289
    • AA 21-119
    • AA 22-301
    • AA 24-290
    • AA 24-365
    • AA 51-160
    • Transcript Variant 1
  • Conjugué
    • His tag
    • His tag,Strep Tag
    • His tag,Strep Tag,AVI tag,Biotin
    • GST tag
    • His-Avi Tag,Biotin
    • Myc-DYKDDDDK Tag
    • Inconjugué
    • His tag,AVI tag,Strep Tag,Biotin
    • His tag,Strep Tag,Biotin
    • His-Avi Tag
    • His-SUMO Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • OriGene
    • Signalway
    • CUSABIO

Dernières publications pour nos neonatal Fc Receptor Protéines

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." dans: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." dans: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." dans: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." dans: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." dans: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." dans: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." dans: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." dans: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Pseudonymes pour neonatal Fc Receptor Protéines

Fc fragment of IgG receptor and transporter (FCGRT) Protéines
Fc fragment of IgG receptor and transporter (Fcgrt) Protéines
Fc receptor, IgG, alpha chain transporter (Fcgrt) Protéines
alpha-chain Protéines
FCRN Protéines
FcRn Protéines
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