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neonatal Fc Receptor Protéines

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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33 Résultats

FcRn Protéine
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
N° du produit ABIN7534672
Détails
Détails
 
FcRn Protein (AA 22-301) (His tag)
FcRn Origine: Souris Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
N° du produit ABIN7607622
Détails
Détails
 
FcRn Protein (AA 22-297) (His-Avi Tag,Biotin)
FcRn Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7504325
Détails
Détails
 
FcRn Protein (His tag)
FcRn Origine: Humain Hôte: Mammalian Cells Recombinant SDS, WB, ELISA
N° du produit ABIN7576943
Détails
Détails
 
FcRn Protein (AA 24-365) (His tag)
FcRn Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
N° du produit ABIN7403297
Détails
Détails
 
FcRn Protein (AA 16-289) (His tag,Strep Tag)
FcRn Origine: Porc Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
N° du produit ABIN4949195
Détails
Détails
 
FcRn Protein (AA 24-297, Extracellular) (GST tag)
FcRn Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709509
Détails
Détails
 
FcRn Protein (AA 24-297, Extracellular) (His tag)
FcRn Origine: Humain Hôte: Levure Recombinant > 90 % SDS
N° du produit ABIN5713450
Détails
Détails
 
FcRn Protein (AA 24-297, Extracellular) (His-SUMO Tag)
FcRn Origine: Cynomolgus Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5711682
Détails
Détails
 
FcRn Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2720990
Détails
Détails
 
FcRn Protein (AA 24-297) (His tag)
FcRn Origine: Cynomolgus Hôte: Levure Recombinant > 90 % ELISA
N° du produit ABIN1643585
Détails
Détails
 
FcRn Protein (Transcript Variant 2)
FcRn Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2720991
Détails
Détails
 
FcRn Protein (AA 23-298) (His tag)
FcRn Origine: Rat Hôte: Levure Recombinant > 90 % ELISA
N° du produit ABIN1473931
Détails
Détails
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
    • Immunogen (Imm)
    • Size-exclusion chromatography-High Pressure Liquid Chromatography (SEC-HPLC)
    • Surface Plasmon Resonance (SPR)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Positive Control (PC)
  • Réactivité
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rhesus Monkey
    • Pig
  • Cité dans publications
  • Images disponible
  • Sans conservateur uniquement
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Human Cells
    • Wheat germ
  • Epitope
    • AA 24-297
    • AA 22-297
    • AA 23-298
    • Extracellular
    • Transcript Variant 2
    • AA 16-289
    • AA 21-119
    • AA 22-301
    • AA 24-290
    • AA 24-365
    • AA 51-160
    • Transcript Variant 1
  • Conjugué
    • His tag
    • His tag,Strep Tag
    • His tag,Strep Tag,AVI tag,Biotin
    • GST tag
    • His-Avi Tag,Biotin
    • Myc-DYKDDDDK Tag
    • Inconjugué
    • His tag,AVI tag,Strep Tag,Biotin
    • His tag,Strep Tag,Biotin
    • His-Avi Tag
    • His-SUMO Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • OriGene
    • Signalway
    • CUSABIO

Dernières publications pour nos neonatal Fc Receptor Protéines

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." dans: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." dans: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." dans: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." dans: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." dans: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." dans: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." dans: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." dans: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." dans: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Pseudonymes pour neonatal Fc Receptor Protéines

Fc fragment of IgG receptor and transporter (FCGRT) Protéines
Fc fragment of IgG receptor and transporter (Fcgrt) Protéines
Fc receptor, IgG, alpha chain transporter (Fcgrt) Protéines
alpha-chain Protéines
FCRN Protéines
FcRn Protéines

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