NFYA Produits
(Nuclear Transcription Factor Y, alpha (NFYA))
Catégories
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008].
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Catégories NFYA en vedette
NFYA Anticorps
High quality antibodies with extensive validation data.
NFYA Kits ELISA
Reliable ELISA kits for a wide range of species.
NFYA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NFYA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6257371
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN6735785
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (1)
N° du produit
ABIN104769
Quantité
100 μg
Fiche technique
Fiche technique
NFYA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
N° du produit
ABIN5648500
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative DNA-Binding ELISA
Validations
N° du produit
ABIN5526700
Quantité
96 tests
Fiche technique
Fiche technique
NFYA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124216
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312515
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312517
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NFYA
: "p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma." dans: Molecular cancer, Vol. 18, Issue 1, pp. 38, (2019) (PubMed).: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).
: "Regulation of the p53 transcriptional response by structurally diverse core promoters." dans: Genes & development, Vol. 24, Issue 2, pp. 135-47, (2010) (PubMed).
: "Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity." dans: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5203-13, (2008) (PubMed).
: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." dans: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).
: "Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver." dans: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15628-37, (2008) (PubMed).
: "Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 984-94, (2008) (PubMed).
: "Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site." dans: Journal of cellular physiology, Vol. 211, Issue 1, pp. 183-8, (2007) (PubMed).
: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." dans: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).
: "Transcriptional modulation of the pre-implantation embryo-specific Rnf35 gene by the Y-box protein NF-Y/CBF." dans: The Biochemical journal, Vol. 387, Issue Pt 2, pp. 367-75, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à NFYA
nuclear transcription factor Y, alpha (nfya), nuclear transcription factor Y subunit alpha (NFYA), nuclear transcription factor-Y alpha (Nfya), nuclear transcription factor Y subunit alpha (Nfya), AA407810, CBF-A, CBF-B, Cbf-b, HAP2, ik:tdsubc_2b6, NF-YA, NFYA, SEZ-10, SEZ10, wu:fb16e03, xx:tdsubc_2b6Protein level used designations for NFYA
- fb16e03
- tdsubc_2b6
- nuclear transcription factor Y, alpha
- CAAT box DNA-binding protein subunit A
- CAAT-box DNA binding protein subunit A
- CCAAT-binding transcription factor subunit B
- HAP2 CCAAT-binding protein
- Transcription factor NF-Y, A subunit
- nuclear transcription factor Y subunit A
- nuclear transcription factor Y subunit alpha
- CAAT-box DNA-binding protein subunit A
- NF-Y protein chain A
- nuclear transcription factor-Y alpha
- NF-YA
- CBF-B
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