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NOD1 Produits

(Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))

Catégories

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009].

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Catégories NOD1 en vedette

NOD1 Anticorps

High quality antibodies with extensive validation data.

NOD1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NOD1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NOD1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (5)
N° du produit ABIN3021838
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC (p), ICC
Validations
  • (6)
N° du produit ABIN3032080
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (1)
  • (3)
N° du produit ABIN872332
Quantité 100 μL
Fiche technique Fiche technique

NOD1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974816
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1145825
Quantité 96 tests
Fiche technique Fiche technique

NOD1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312761
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312759
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312757
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NOD1

Guo, Li, Zhou, Li, Lyu, Chen, Lyu, Tian, Yuan, Ran, Chen, Jiang, Li: "Evodiamine Induces Apoptosis in SMMC-7721 and HepG2 Cells by Suppressing NOD1 Signal Pathway." dans: International journal of molecular sciences, Vol. 19, Issue 11, (2019) (PubMed).

Hosokawa, Hirao, Yumoto, Washio, Nakanishi, Takegawa, Kitamura, Matsuo: "Functional Roles of NOD1 in Odontoblasts on Dental Pulp Innate Immunity." dans: BioMed research international, Vol. 2016, pp. 9325436, (2016) (PubMed).

Asano, Imatani, Watanabe, Fushiya, Kondo, Jin, Ara, Uno, Iijima, Koike, Strober, Shimosegawa: "Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses." dans: Cancer research, Vol. 76, Issue 5, pp. 1135-45, (2016) (PubMed).

Arentsen, Qian, Gkotzis, Femenia, Wang, Udekwu, Forssberg, Diaz Heijtz: "The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." dans: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, (2016) (PubMed).

Necchi, Sommi, Vanoli, Manca, Ricci, Solcia: "Proteasome particle-rich structures are widely present in human epithelial neoplasms: correlative light, confocal and electron microscopy study." dans: PLoS ONE, Vol. 6, Issue 6, pp. e21317, (2011) (PubMed).

Scott, Chen, Sun, Billiar: "Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production." dans: Journal of hepatology, Vol. 53, Issue 4, pp. 693-701, (2010) (PubMed).

Lu, Zou, Feng, Yuan, Gu, Li, Li, Jin, Li: "Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: a meta-analysis." dans: World journal of gastroenterology, Vol. 16, Issue 34, pp. 4348-56, (2010) (PubMed).

Liu, Yan, Liu, Wang, Li, Deng, Singh, Coleman, Rodgers: "Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 11056-61, (2010) (PubMed).

King, Horne, Hombach-Klonisch, Mason, Critchley: "Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation." dans: Molecular human reproduction, Vol. 15, Issue 5, pp. 311-9, (2009) (PubMed).

Swaan, Bensman, Bahadduri, Hall, Sarkar, Bao, Khantwal, Ekins, Knoell: "Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2." dans: American journal of respiratory cell and molecular biology, Vol. 39, Issue 5, pp. 536-42, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à NOD1

nucleotide binding oligomerization domain containing 1 (NOD1), nucleotide-binding oligomerization domain containing 1 (Nod1), C230079P11, CARD4, Card4, CLR7.1, F830007N14Rik, NLRC1, Nlrc1, RGD1562269

Protein level used designations for NOD1

  • NLR family, CARD domain containing 1
  • caspase recruitment domain family, member 4
  • caspase recruitment domain-containing protein 4
  • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
  • nucleotide-binding oligomerization domain-containing protein 1
  • caspase recruitment domain 4
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