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NR2F6 Protéines

(Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock\; is required early in the development of the locus coeruleus (LC).

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NR2F6 Protein (AA 1-390) (His tag)

custom-made NR2F6 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Nr2f6 Protein, UniprotID P43136

3 images

N° du produit ABIN7563256

Détails

NR2F6 Protein (AA 1-404) (His tag)

custom-made NR2F6 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant NR2F6 Protein, UniprotID P10588

3 images

N° du produit ABIN7554787

Détails

NR2F6 Protein (AA 1-404) (His tag)

NR2F6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 1-404) protein (His tag) (ABIN7124214)

1 image

N° du produit ABIN7124214

Détails

NR2F6 Protein (AA 1-404) (GST tag)

NR2F6 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 1-404) protein (GST tag) (ABIN1989628)

1 image

N° du produit ABIN1989628

Détails

NR2F6 Protein (AA 1-390) (Strep Tag)

custom-made NR2F6 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3134056

Détails

NR2F6 Protein (AA 1-404) (Strep Tag)

custom-made NR2F6 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3094228