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NUAK1 Protéines

(NUAK Family, SNF1-Like Kinase, 1 (NUAK1))

Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in 392' and is recruited to the CDKN1A/WAF1 promoter to participate to transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR.

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NUAK1 Protein (AA 1-658) (His tag)

custom-made NUAK1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Nuak1 Protein, UniprotID Q641K5

3 images

N° du produit ABIN7563982

Détails

NUAK1 Protein (AA 1-661) (His tag)

custom-made NUAK1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant NUAK1 Protein, UniprotID O60285

3 images

N° du produit ABIN7554818

Détails

NUAK1 Protein (AA 371-470) (GST tag)

NUAK1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 371-470) protein (GST tag) (ABIN1313130)

1 image

N° du produit ABIN1313130

Détails

NUAK1 Protein (AA 1-661) (GST tag)

NUAK1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 1-661) protein (GST tag) (ABIN1313129)

1 image

N° du produit ABIN1313129

Détails

NUAK1 Protein (GST tag)

NUAK1 Origine: Humain Hôte: Cellules d'insectes Recombinant 70 % - 90 % Func Active

N° du produit ABIN5509049

Détails

NUAK1 Protein (AA 465-661) (His-IF2DI Tag)

NUAK1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

N° du produit ABIN7664825

Détails

NUAK1 Protein (AA 421-658) (His tag)

NUAK1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

N° du produit ABIN7416934

Détails

NUAK1 Protein (AA 404-651) (His tag,GST tag)

NUAK1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

N° du produit ABIN7417036

Détails

NUAK1 Protein (AA 1-658) (Strep Tag)

custom-made NUAK1 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3135583

Détails

NUAK1 Protein (AA 1-661) (Strep Tag)

custom-made NUAK1 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3094295