PDL1 Detection Set (Risk Free)
Aperçu rapide pour PDL1 Detection Set (Risk Free) (ABIN6251785)
Antigène
Épitope
Reactivité
Hôte
Clonalité
Application
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Marque
- Risk-Free™
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Attributs du produit
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
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Purification
- Antibodies are supplied as protein A purified IgG1.
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Ingrédients
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PD-L1 Antibody [4F2]
PD-L1 Antibody [8E12]
PD-L1 Antibody [6H10]
PD-L1 Antibody [2D6]
PD-L1 Antibody [1F11]
PD-L1 Antibody [1D7] -
Immunogène
- PD-L1 antibodies were raised against the extracellular domain of human PD-L1.
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Isotype
- IgG1
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CD274 (Human) Matched Antibody Pair
ELISA Reactivité: Humain ELISA unconjugated Hôte: Souris
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Commentaires
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Risk-Free™ antibodies are monoclonal antibodies made to improve in vitro studies.
Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
These antibodies have the following advantages:
- Antibodies are developed against mammalian-expressed, post-translationally modified recombinant proteins.
- Multiple antibodies per target allows the user to choose the best antibody for their application
- Available individually or as a set
- Risk-Free™ means they are rigorously tested and guaranteed to work for their designated applications:
- ELISA
- Flow Cytometry
- Immunoblot
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PD-L1 (CD274 (PD-L1))
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Autre désignation
- PDL1
Antigène
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