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PD-L1 Protéines

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

80 Résultats

PD-L1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
N° du produit ABIN1348592
 
PD-L1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
N° du produit ABIN7194779
 
PD-L1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
N° du produit ABIN6386958
 
PD-L1 Origine: Cynomolgus Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7538168
 
PD-L1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS, AcA Active
N° du produit ABIN7281265
 
PD-L1 Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2181635
 
PD-L1 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN7013168
 
PD-L1 Origine: Cynomolgus, Macaque rhésus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2181633
 
PD-L1 Origine: Souris Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2870578
 
PD-L1 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6810006
 
PD-L1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505141
 
PD-L1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318878
 
PD-L1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318879
 
PD-L1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1096071
 
PD-L1 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN4371365
 
PD-L1 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN4371362
 
PD-L1 Origine: Rat Hôte: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7663068
 
PD-L1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN4371782
 
PD-L1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN4371704
 
PD-L1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7454090
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Protein Interaction (PI)
  • Réactivité
    • Human
    • Mouse
    • Cynomolgus
    • Rhesus Monkey
    • Dog
    • Rat
    • Rabbit
  • Cité dans publications
  • Images disponible
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • CHO Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • Epitope
    • AA 19-238
    • AA 19-239
    • AA 1-239
    • AA 18-238
    • AA 19-134
    • AA 19-237
    • AA 34-241
    • partial
    • AA 1-238
    • AA 128-238
    • AA 141-240
    • AA 19-132
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • Conjugué
    • His tag
    • Fc Tag
    • Inconjugué
    • DYKDDDDK Tag
    • mFc Tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His tag,Biotin
    • His-Avi Tag,Biotin
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His-DYKDDDDK-Strep II Tag
    • His-IF2DI Tag
    • Llama Fc Tag
    • SUMO Tag
    • Strep Tag
    • Twin-Strep tag
    • hIgG-His-tag
    • mFc-His Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Activité biologique
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • OriGene
    • Cohesion Biosciences
    • ProteoGenix

Dernières publications pour nos PD-L1 Protéines

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." dans: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." dans: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." dans: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." dans: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." dans: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." dans: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." dans: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." dans: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." dans: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." dans: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Pseudonymes pour PD-L1 Protéines

CD274 molecule (CD274) Protéines
CD274 antigen (Cd274) Protéines
programmed cell death 1 ligand 2 (PDCD1LG2) Protéines
CD274 molecule (Cd274) Protéines
A530045L16Rik Protéines
B7-H Protéines
B7H1 Protéines
B7h1 Protéines
PD-L1 Protéines
PDCD1L1 Protéines
Pdcd1l1 Protéines
PDCD1LG1 Protéines
Pdcd1lg1 Protéines
PDL1 Protéines
Pdl1 Protéines
RGD1566211 Protéines
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