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Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide

PTF1A Reactivité: Humain, Souris Hôte: Synthetic BP, WB
N° du produit ABIN1540933
  • Antigène Tous les produits PTF1A
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    Protein Region
    N-Term
    Origine
    Humain, Souris
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-Ptf1a Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    Synonymes
    PTF1A Peptide, PTF1 Peptide, si:zc142h2.2 Peptide, zgc:112216 Peptide, Ptf1a/p48 Peptide, XPtf1a Peptide, PTF1-p48 Peptide, bHLHa29 Peptide, PTF1p48 Peptide, pancreas specific transcription factor, 1a Peptide, PTF1A Peptide, ptf1a Peptide, Ptf1a Peptide
    Sujet
    Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.

    Alias Symbols: PTF1-p48, PTF1p48, bHLHa29

    Protein Size: 324
    Poids moléculaire
    35 kDa
    ID gène
    19213
    NCBI Accession
    NM_018809, NP_061279
    UniProt
    Q9QX98
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