Histamine Receptor H3 (HRH3) (N-Term) Peptide
HRH3
Reactivité: Humain, Rat
Hôte: Synthetic
BP, WB
N° du produit ABIN1541323
Aperçu rapide pour Histamine Receptor H3 (HRH3) (N-Term) Peptide (ABIN1541323)
Antigène
HRH3
(Histamine Receptor H3 (HRH3))
Origine
Humain, Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- VFNIVLISYD RFLSVTRAVS YRAQQGDTRR AVRKMALVWV LAFLLYGPAI
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Hrh3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HRH3 (Histamine Receptor H3 (HRH3))
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Sujet
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This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene.
Alias Symbols: -
Protein Size: 445 -
Poids moléculaire
- 48 kDa
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ID gène
- 85268
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NCBI Accession
- NM_053506, NP_445958
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UniProt
- Q9QYN8
Antigène
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