Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide
CCR2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2183653
Aperçu rapide pour Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide (ABIN2183653)
Antigène
CCR2
(Chemokine (C-C Motif) Receptor 2 (CCR2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- RSRFIRNTNE SGEEVTTFFD YDYGAPCHKF DVKQIGAQLL PPLYSLVFIF
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Sujet
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Alias Symbols: CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Protein Size: 360 -
Poids moléculaire
- 39 kDa
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ID gène
- 729230
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NCBI Accession
- NM_001123396, NP_001116868
Antigène
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