Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Corticotropin Releasing Hormone (CRH) (C-Term) Peptide

CRH Reactivité: Humain Hôte: Synthetic WB, BP
N° du produit ABIN2184150

Aperçu rapide pour Corticotropin Releasing Hormone (CRH) (C-Term) Peptide (ABIN2184150)

Antigène

CRH (Corticotropin Releasing Hormone (CRH))

Origine

Humain

Source

  • 16
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    C-Term

    Séquence

    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    CRH (Corticotropin Releasing Hormone (CRH))

    Sujet

    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196

    Poids moléculaire

    21 kDa

    ID gène

    1392

    NCBI Accession

    NM_000756, NP_000747

    UniProt

    P06850
Vous êtes ici:
Chat with us!