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Corticotropin Releasing Hormone (CRH) (C-Term) Peptide

CRH Reactivité: Humain Hôte: Synthetic WB, BP
N° du produit ABIN2184150
  • Antigène Tous les produits CRH
    CRH (Corticotropin Releasing Hormone (CRH))
    Protein Region
    C-Term
    Origine
    Humain
    Source
    • 16
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Séquence
    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CRH (Corticotropin Releasing Hormone (CRH))
    Synonymes
    CRF Peptide, Gm1347 Peptide, crf Peptide, crh Peptide, zgc:101864 Peptide, CRH Peptide, corticoliberin Peptide, crhb Peptide, crh.1-a Peptide, crha Peptide, corticotropin releasing hormone Peptide, corticotropin releasing hormone b Peptide, corticotropin releasing hormone S homeolog Peptide, corticotropin releasing hormone L homeolog Peptide, Crh Peptide, CRH Peptide, crhb Peptide, crh Peptide, crh.S Peptide, crh.L Peptide
    Sujet
    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196
    Poids moléculaire
    21 kDa
    ID gène
    1392
    NCBI Accession
    NM_000756, NP_000747
    UniProt
    P06850
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