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GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptide

GRAP Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN2184413
  • Antigène Tous les produits GRAP
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
    Attributs du produit
    This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
  • Antigène
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Synonymes
    8430435N19Rik Peptide, BB233594 Peptide, GRAP Peptide, grap Peptide, zgc:110202 Peptide, MGC109892 Peptide, si:dkeyp-9d4.1 Peptide, Grap Peptide, GRB2-related adaptor protein Peptide, GRB2-related adapter protein Peptide, GRB2-related adaptor protein a Peptide, GRB2-related adaptor protein b Peptide, GRAP Peptide, Grap Peptide, LOC489534 Peptide, grapa Peptide, grapb Peptide, LOC100727005 Peptide
    Sujet
    This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

    Alias Symbols: -

    Protein Size: 217
    Poids moléculaire
    25 kDa
    ID gène
    10750
    NCBI Accession
    NM_006613, NP_006604
    UniProt
    Q13588
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