Lysine (K)-Specific Demethylase 2A (KDM2A) (Middle Region) Peptide
KDM2A
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2184592
Aperçu rapide pour Lysine (K)-Specific Demethylase 2A (KDM2A) (Middle Region) Peptide (ABIN2184592)
Antigène
KDM2A
(Lysine (K)-Specific Demethylase 2A (KDM2A))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Séquence
- LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-KDM2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
-
Sujet
-
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
Protein Size: 620 -
Poids moléculaire
- 68 kDa
-
ID gène
- 22992
-
NCBI Accession
- NM_012308, NP_036440
Antigène
-
Vous êtes ici:
