Synovial Sarcoma, X Breakpoint 2 (SSX2) (Middle Region) Peptide
SSX2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2184613
Aperçu rapide pour Synovial Sarcoma, X Breakpoint 2 (SSX2) (Middle Region) Peptide (ABIN2184613)
Antigène
SSX2
(Synovial Sarcoma, X Breakpoint 2 (SSX2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- TFGRLQGISP KIMPKKPAEE G NDSEEVPEAS GPQNDGKELC PPGKPTTS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SSX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
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Sujet
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SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CT5.2a, HD21, HOM-MEL-40, SSX
Protein Size: 223 -
Poids moléculaire
- 24 kDa
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ID gène
- 6757
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NCBI Accession
- NM_175698, NP_783629
Antigène
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