GTP Cyclohydrolase 1 (GCH1) (N-Term) Peptide
GCH1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2185568
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour GTP Cyclohydrolase 1 (GCH1) (N-Term) Peptide (ABIN2185568)
Antigène
GCH1
(GTP Cyclohydrolase 1 (GCH1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- PPRPEAKSAQ PADGWKGERP RSEEDNELNL PNLAAAYSSI LSSLGENPQR
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GCH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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GTP Cyclohydrolase 1 (GCH1) peptide
GCH1 Reactivité: Humain, Souris, Rat Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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Sujet
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This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Protein Size: 250 -
Poids moléculaire
- 27 kDa
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ID gène
- 2643
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UniProt
- P30793
Antigène
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