F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide
Aperçu rapide pour F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide (ABIN2763846)
Antigène
Origine
Source
Application
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Restrictions
- For Research Use only
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Stock
- -80 °C
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Sujet
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Antigène
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