(1 reference)
N° du produit ABIN399149
Aperçu rapide pour Amyloid beta (Abeta) (AA 25-35) Peptide (ABIN399149)
Antigène
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
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Protein Region
- AA 25-35
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Pureté
- > 95 %
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Restrictions
- For Research Use only
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Stock
- -20 °C
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." dans: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." dans: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Sujet
- Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
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Numéro CAS
- 131602-53-4
Antigène
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