(1 reference)-
- Antigène Tous les produits beta Amyloid (Abeta)
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Protein Region
- AA 25-35
- Pureté
- > 95 %
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- Restrictions
- For Research Use only
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- Stock
- -20 °C
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." dans: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." dans: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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- Antigène
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Synonymes
- AAA Peptide, ABETA Peptide, ABPP Peptide, AD1 Peptide, APPI Peptide, CTFgamma Peptide, CVAP Peptide, PN-II Peptide, PN2 Peptide, aaa Peptide, abeta Peptide, abpp Peptide, ad1 Peptide, appi Peptide, ctfgamma Peptide, cvap Peptide, pn2 Peptide, Abeta Peptide, Abpp Peptide, Adap Peptide, Ag Peptide, Cvap Peptide, E030013M08Rik Peptide, betaApp Peptide, amyloid beta precursor protein Peptide, amyloid beta (A4) precursor protein Peptide, APP Peptide, app Peptide, App Peptide
- Sujet
- Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
- Numéro CAS
- 131602-53-4
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