This is a synthetic peptide designed for use in combination with anti-NCEH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
NCEH1 hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. It may be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. NCEH1 also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. It may contribute to cancer pathogenesis by promoting tumor cell migration.