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Activating Transcription Factor 7 (ATF7) (Middle Region) Peptide

ATF7 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5510945

Aperçu rapide pour Activating Transcription Factor 7 (ATF7) (Middle Region) Peptide (ABIN5510945)

Antigène

ATF7 (Activating Transcription Factor 7 (ATF7))

Origine

Humain

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Séquence

    GYDPLHPTLP SPTSVITQAP PSNRQMGSPT GSLPLVMHLA NGQTMPVLPG

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-ATF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    ATF7 (Activating Transcription Factor 7 (ATF7))

    Sujet

    Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. FUNCTION: Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter.ATF7 Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.

    Alias Symbols: ATF7,ATFA,

    Protein Size: 473

    ID gène

    11016
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