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Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) Peptide

BMPR1A Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5510994

Aperçu rapide pour Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) Peptide (ABIN5510994)

Antigène

BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Origine

Humain

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-BMPR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

    Sujet

    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    Alias Symbols: BMPR1A,ACVRLK3,ALK3,

    Protein Size: 532

    ID gène

    657

    NCBI Accession

    XP_005270121

    UniProt

    P36894
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