This is a synthetic peptide designed for use in combination with anti-BMPR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
BMPR1A
(Bone Morphogenetic Protein Receptor 1A (BMPR1A))
Synonymes
10q23del Peptide, ACVRLK3 Peptide, ALK3 Peptide, CD292 Peptide, SKR5 Peptide, 1110037I22Rik Peptide, AU045487 Peptide, BMPR-IA Peptide, Bmpr Peptide, BMPR-1 Peptide, BRK-1 Peptide, BMPR1A Peptide, acvrlk3 Peptide, alk-3 Peptide, alk3 Peptide, cd292 Peptide, skr5 Peptide, BR1a Peptide, alk3tr Peptide, bmpr1a Peptide, zgc:136731 Peptide, wu:fe05b06 Peptide, wu:fe06e10 Peptide, zgc:92227 Peptide, bone morphogenetic protein receptor type 1A Peptide, bone morphogenetic protein receptor, type 1A Peptide, bone morphogenetic protein receptor type 1A S homeolog Peptide, bone morphogenetic protein receptor, type IAa Peptide, bone morphogenetic protein receptor, type IAb Peptide, BMPR1A Peptide, Bmpr1a Peptide, bmpr1a Peptide, bmpr1a.S Peptide, bmpr1aa Peptide, bmpr1ab Peptide
Sujet
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.