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Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide

CARD11 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5511030
  • Antigène Tous les produits CARD11
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Synonymes
    BENTA Peptide, BIMP3 Peptide, CARMA1 Peptide, PPBL Peptide, 0610008L17Rik Peptide, 2410011D02Rik Peptide, CARD11 Peptide, LOC100232755 Peptide, caspase recruitment domain family member 11 Peptide, caspase recruitment domain family, member 11 Peptide, caspase recruitment domain-containing protein 11 Peptide, CARD11 Peptide, Card11 Peptide, LOC100550812 Peptide, card11 Peptide
    Sujet
    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1

    Protein Size: 1171
    ID gène
    84433
    NCBI Accession
    NM_032415, NP_115791
    UniProt
    Q8TES3
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