Caspase Recruitment Domain Family, Member 8 (CARD8) (N-Term) Peptide
CARD8
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511031
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 21 jours ouvrables
Aperçu rapide pour Caspase Recruitment Domain Family, Member 8 (CARD8) (N-Term) Peptide (ABIN5511031)
Antigène
CARD8
(Caspase Recruitment Domain Family, Member 8 (CARD8))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CARD8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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Sujet
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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Protein Size: 286 -
ID gène
- 22900
Antigène
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