Polycomb Group Ring Finger 2 (PCGF2) (Middle Region) Peptide
PCGF2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511130
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Polycomb Group Ring Finger 2 (PCGF2) (Middle Region) Peptide (ABIN5511130)
Antigène
PCGF2
(Polycomb Group Ring Finger 2 (PCGF2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- EQEKGALSDD EIVSLSIEFY EGARDRDEKK GPLENGDGDK EKTGVRFLRC
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PCGF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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Sujet
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The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
Alias Symbols: MEL-18, RNF110, ZNF144
Protein Size: 344 -
ID gène
- 7703
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NCBI Accession
- NM_007144, NP_009075
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UniProt
- P35227
Antigène
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