Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide
LZTS1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511174
Aperçu rapide pour Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide (ABIN5511174)
Antigène
LZTS1
(Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG KSEDFFYIKV SQKARGSHHP
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-LZTS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
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Sujet
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This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Alias Symbols: LZTS1, FEZ1,
Protein Size: 596 -
ID gène
- 11178
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NCBI Accession
- XP_005273451
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UniProt
- Q9Y250
Antigène
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