Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptide
Aperçu rapide pour Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptide (ABIN5511361)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Séquence
- NVRTQVAADW TALAEEMDFE YLEIRQLETQ ADPTGRLLDA WQGRPGASVG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MYD88 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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Sujet
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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Alias Symbols: MYD88D
Protein Size: 296 -
ID gène
- 4615
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NCBI Accession
- NM_001172566, NP_001166037
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UniProt
- Q99836
Antigène
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