Nibrin (NBN) (Middle Region) Peptide
NBN
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits Nibrin (NBN)
- Nibrin (NBN)
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- TGLKTTTPGP SLSQGVSVDE KLMPSAPVNT TTYVADTESE QADTWDLSER
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Nibrin (NBN)
- Synonymes
- NBN Peptide, AT-V1 Peptide, AT-V2 Peptide, ATV Peptide, NBS Peptide, NBS1 Peptide, P95 Peptide, Nbs1 Peptide, im:6911679 Peptide, zgc:194152 Peptide, nibrin Peptide, NBN Peptide, nbn Peptide, Nbn Peptide
- Sujet
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Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Protein Size: 754 - ID gène
- 4683
- UniProt
- O60934
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