OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptide
OTUB1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511414
Aperçu rapide pour OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptide (ABIN5511414)
Antigène
OTUB1
(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-OTUB1 antibody (Catalog #: ARP59280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) peptide
OTUB1 Reactivité: Humain, Souris, Boeuf (Vache), Rat Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Sujet
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Alias Symbols: OTB1, OTU1
Protein Size: 271 -
Poids moléculaire
- 29 kDa
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ID gène
- 55611
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NCBI Accession
- NP_060140
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UniProt
- Q96FW1
Antigène
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