Paraoxonase 2 (PON2) (Middle Region) Peptide
Aperçu rapide pour Paraoxonase 2 (PON2) (Middle Region) Peptide (ABIN5511445)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Séquence
- LDTLVDNLSI DPSSGDIWVG CHPNGQKLFV YDPNNPPSSE VLRIQNILCE
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- PON2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PON2 (Paraoxonase 2 (PON2))
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Sujet
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This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Size: 354 -
ID gène
- 5445
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NCBI Accession
- NM_000305, NP_000296
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UniProt
- Q15165
Antigène
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