5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (Middle Region) Peptide
MTRR
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512111
Aperçu rapide pour 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (Middle Region) Peptide (ABIN5512111)
Antigène
MTRR
(5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- LQPNIHASHE DSGKALAPKI SISPRTTNSF HLPDDPSIPI IMVGPGTGIA
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MTRR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
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Sujet
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Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: MTRR,
Protein Size: 698 -
ID gène
- 4552
Antigène
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