Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide
ALAD
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512124
Aperçu rapide pour Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide (ABIN5512124)
Antigène
ALAD
(Aminolevulinate Dehydratase (ALAD))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ALAD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALAD (Aminolevulinate Dehydratase (ALAD))
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Sujet
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: PBGS, ALADH
Protein Size: 330 -
ID gène
- 210
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NCBI Accession
- NM_000031, NP_000022
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UniProt
- P13716
Antigène
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