TRAF3 Interacting Protein 2 (TRAF3IP2) (Middle Region) Peptide
Aperçu rapide pour TRAF3 Interacting Protein 2 (TRAF3IP2) (Middle Region) Peptide (ABIN5512149)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Séquence
- DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR AGAPGESLEC PAELRPQVPQ
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- TRAF3IP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
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Sujet
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This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Alias Symbols: ACT1, CIKS, C6orf2, C6orf4, C6orf5, C6orf6, CANDF8, PSORS13
Protein Size: 574 -
ID gène
- 10758
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NCBI Accession
- NM_001164281, NP_001157753
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UniProt
- O43734
Antigène
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