Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) Peptide
CCR3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512183
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) Peptide (ABIN5512183)
Antigène
CCR3
(Chemokine (C-C Motif) Receptor 3 (CCR3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- ERFRKYLRHF FHRHLLMHLG RYIPFLPSEK LERTSSVSPS TAEPELSIVF
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- CCR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Sujet
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The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Alias Symbols: CKR3, CD193, CMKBR3, CC-CKR-3
Protein Size: 355 -
ID gène
- 1232
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NCBI Accession
- NM_001837, NP_001828
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UniProt
- P51677
Antigène
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