Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptide
HSD17B10
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512376
Aperçu rapide pour Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptide (ABIN5512376)
Antigène
HSD17B10
(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- IRLVAGEMGQ NEPDQGGQRG VIINTASVAA FEGQVGQAAY SASKGGIVGM
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- HSD17B10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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Sujet
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This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22
Protein Size: 261 -
ID gène
- 3028
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NCBI Accession
- NM_001037811, NP_001032900
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UniProt
- Q99714
Antigène
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