Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) (Middle Region) Peptide
PLAGL1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits PLAGL1
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LPESLASLHP SVSPGSPPPP LPNHKYNTTS TSYSPLASLP LKADTKGFCN
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PLAGL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
- Synonymes
- PLAGL1 Peptide, LOT1 Peptide, ZAC Peptide, ZAC1 Peptide, Lot1 Peptide, Zac1 Peptide, PLAG1 like zinc finger 1 Peptide, uncharacterized LOC100350914 Peptide, pleiomorphic adenoma gene-like 1 Peptide, PLAGL1 Peptide, LOC100350914 Peptide, Plagl1 Peptide
- Sujet
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This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.
Alias Symbols: ZAC, LOT1, ZAC1
Protein Size: 411 - ID gène
- 5325
- NCBI Accession
- NM_001080951, NP_001074420
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