Chitotriosidase (CHIT1) (C-Term) Peptide
CHIT1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512621
Aperçu rapide pour Chitotriosidase (CHIT1) (C-Term) Peptide (ABIN5512621)
Antigène
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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Sujet
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Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 -
ID gène
- 1118
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NCBI Accession
- NM_001256125, NP_001243054
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UniProt
- Q13231
Antigène
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