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NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide

NSUN2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5513462

Aperçu rapide pour NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide (ABIN5513462)

Antigène

NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Origine

Humain

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-NSUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

    Sujet

    NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

    Alias Symbols: NSUN2,SAKI, TRM4,

    Protein Size: 767

    ID gène

    54888

    NCBI Accession

    NP_060225

    UniProt

    Q08J23
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