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Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide

TMED10 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5513592
  • Antigène Tous les produits TMED10
    TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTRVLY
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti- TMED10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
    Synonymes
    tmp21 Peptide, P24(DELTA) Peptide, S31I125 Peptide, S31III125 Peptide, TMP21 Peptide, Tmp-21-I Peptide, p23 Peptide, 1110014C03Rik Peptide, Tmp21 Peptide, p24delta1 Peptide, fe06g04 Peptide, wu:fb98e10 Peptide, wu:fe06g04 Peptide, zgc:85681 Peptide, transmembrane p24 trafficking protein 10 L homeolog Peptide, transmembrane p24 trafficking protein 10 Peptide, tmed10.L Peptide, TMED10 Peptide, Tmed10 Peptide, tmed10 Peptide
    Sujet
    This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

    Alias Symbols: p23, TMP21, S31I125, Tmp-21-I, S31III125, P24(DELTA)

    Protein Size: 219
    ID gène
    10972
    NCBI Accession
    NM_006827, NP_006818
    UniProt
    P49755
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