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Transmembrane Protease, serine 2 (TMPRSS2) (Middle Region) Peptide

TMPRSS2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5513593
  • Antigène Tous les produits TMPRSS2
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    SFMFYGAGYQ VEKVISHPNY DSKTKNNDIA LMKLQKPLTF NDLVKPVCLP
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti- TMPRSS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    Synonymes
    PP9284 Peptide, PRSS10 Peptide, D16Ertd61e Peptide, transmembrane protease serine 2-like Peptide, transmembrane protease, serine 2 Peptide, LOC100739411 Peptide, TMPRSS2 Peptide, Tmprss2 Peptide
    Sujet
    This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PP9284, PRSS10

    Protein Size: 492
    ID gène
    7113
    NCBI Accession
    NM_001135099, NP_001128571
    UniProt
    O15393
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