Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) Peptide
MAPK10
Reactivité: Humain
Hôte: Synthetic
WB
N° du produit ABIN5518173
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) Peptide (ABIN5518173)
Antigène
MAPK10
(Mitogen-Activated Protein Kinase 10 (MAPK10))
Origine
Humain
Source
Synthetic
Application
Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Séquence
- VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
-
Sujet
-
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
Protein Size: 167 -
ID gène
- 5602
-
NCBI Accession
- NM_002753, NP_002744
-
UniProt
- P53779
Antigène
-
Vous êtes ici:
