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Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Middle Region) Peptide

SIGLEC8 Reactivité: Humain Hôte: Synthetic WB
N° du produit ABIN5518360
  • Antigène Tous les produits SIGLEC8
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Western Blotting (WB)
    Séquence
    VRSCRKKSAR PAAGVGDTGM EDAKAIRGSA SQGPLTESWK DGNPLKKPPP
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Synonymes
    SAF2 Peptide, SIGLEC-8 Peptide, SIGLEC8L Peptide, SIGLEC8 Peptide, sialic acid binding Ig like lectin 8 Peptide, sialic acid-binding Ig-like lectin 8 Peptide, SIGLEC8 Peptide, LOC506364 Peptide
    Sujet
    Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]

    Alias Symbols: SAF2, SIGLEC-8, SIGLEC8L

    Protein Size: 201
    ID gène
    27181
    NCBI Accession
    NM_014442, NP_055257
    UniProt
    Q9NYZ4
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